Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.48 |
| ▸ | DRD3 | P35462 | 6/20 | 0.48 |
| ▸ | DRD4 | P21917 | 5/20 | 0.48 |
| ▸ | DRD1 | P21728 | 3/20 | 0.48 |
| ▸ | DRD5 | P21918 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10373192 | 0.80 | DRD2 (0.54) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL2918145 | 0.80 | HTR2C (0.43) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL28154656 | 0.77 | HTR2C (0.41) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL2187122 | 0.76 | ALDH1A1 (0.37) | — | |
| SCHEMBL16957586 | 0.76 | HDAC4 (0.42) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL16951187 | 0.76 | TP53 (0.47) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL14530044 | 0.76 | HTR2C (0.40) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL31519011 | 0.76 | TP53 (0.47) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL6935362 | 0.76 | HTR2C (0.52) | DRD2HTR2CSIGMAR1 | |
| SCHEMBL28062510 | 0.75 | ESR2 (0.42) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658604-A | Improvements in or relating to organic compounds | 奇华顿股份有限公司 | 2016-06-08 | — | — | CN | claimed |