Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 9/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29887341 | 1.00 | L3MBTL1 (0.49) | L3MBTL1CYP2C19CHEK1LIMK1MAPK14 | |
| SCHEMBL28827610 | 0.88 | CYP2C19 (0.44) | L3MBTL1CYP2C19CHEK1LIMK1MAPK14 | |
| SCHEMBL29887261 | 0.83 | KCNMA1 (0.44) | L3MBTL1CYP2C19KCNMA1TSHRSMN1; SMN2 | |
| SCHEMBL28827605 | 0.83 | KCNMA1 (0.44) | L3MBTL1CYP2C19KCNMA1TSHRSMN1; SMN2 | |
| SCHEMBL29105064 | 0.81 | GAA (0.39) | L3MBTL1CYP2C19CNR1TSHRSMN1; SMN2 | |
| SCHEMBL30678494 | 0.81 | GAA (0.39) | L3MBTL1CYP2C19CNR1TSHRSMN1; SMN2 | |
| SCHEMBL29887566 | 0.78 | L3MBTL1 (0.52) | L3MBTL1TSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28827609 | 0.78 | L3MBTL1 (0.52) | L3MBTL1TSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23037117 | 0.78 | SLC9A1 (0.58) | CYP2C19KCNMA1TSHRSMN1; SMN2CRHBP | |
| SCHEMBL29105055 | 0.76 | SLC9A1 (0.32) | SLC9A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969901-A | Preparation method of 1,2,4-benzotriazine derivative | 浙江师范大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-114957145-B | 1,2,4-benzotriazine derivative and preparation method thereof | 浙江师范大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-114957145-A | 1,2,4-benzotriazine derivative and preparation method thereof | 浙江师范大学 | 2022-08-30 | — | — | CN | disclosed |