SCHEMBL28828308

SCHEMBL28828308

NC(N)(F)F.Oc1ccc(-c2ccccc2)cc1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.76
APP P05067 3/20 0.59
KDM4E B2RXH2 2/20 0.57
MEN1 O00255 2/20 0.57
ALDH1A1 P00352 2/20 0.57
LMNA P02545 2/20 0.57
GAA P10253 2/20 0.57
MAPT P10636 2/20 0.57
HPGD P15428 2/20 0.57
ALOX12 P18054 2/20 0.57
KMT2A Q03164 2/20 0.57
USP2 O75604 1/20 0.57
HSP90AA1 P07900 1/20 0.57
ALOX15 P16050 1/20 0.57
HTT P42858 1/20 0.57
HSD17B10 Q99714 1/20 0.57
ESR2 Q92731 1/20 0.52
SNCA P37840 1/20 0.50
HSD17B1 P14061 1/20 0.49
HSD17B2 P37059 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL928289 0.87 ALOX5 (1.00) ALOX5APPKDM4EMEN1ALDH1A1
SCHEMBL29848221 0.87 ALOX5 (1.00) ALOX5APPKDM4EMEN1ALDH1A1
Methane SCHEMBL28271157 0.85 ALOX5 (0.95) ALOX5APPKDM4EMEN1ALDH1A1
SCHEMBL27714322 0.85 ALOX5 (0.95) ALOX5APPKDM4EMEN1ALDH1A1
SCHEMBL28053825 0.83 ALOX5 (0.83) ALOX5APPKDM4EMEN1ALDH1A1
SCHEMBL27880220 0.83 ALOX5 (0.83) ALOX5APPKDM4EMEN1ALDH1A1
SCHEMBL28134269 0.83 ALOX5 (0.91) ALOX5APPKDM4EMEN1ALDH1A1
Formaldehyde SCHEMBL28374238 0.81 ALOX5 (0.86) ALOX5APPKDM4EMEN1ALDH1A1
Bicarbonate SCHEMBL11789771 0.81 ALOX5 (0.86) ALOX5APPKDM4EMEN1ALDH1A1
SCHEMBL30016853 0.80 APP (0.90) ALOX5APPKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105579907-A Radiation-sensitive composition and pattern production method TOKYO OHKA KOGYO CO LTD 2016-05-11 CN disclosed