Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 16/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29228294 | 0.90 | SCN9A (0.45) | SCN9ACYP2C9CYP3A4CYP2D6SCN10A | |
| SCHEMBL28828483 | 0.87 | EDNRB (0.42) | LRRK2 | |
| SCHEMBL28828701 | 0.86 | SCN9A (0.41) | SCN9ASCN10AOPRD1 | |
| SCHEMBL28950176 | 0.85 | SCN5A (0.35) | SCN9A | |
| SCHEMBL27212735 | 0.85 | EPHX2 (0.37) | SCN9A | |
| SCHEMBL28828631 | 0.85 | ACMSD (0.37) | LRRK2OPRD1 | |
| SCHEMBL28828705 | 0.84 | PTPRC (0.44) | — | |
| SCHEMBL28950165 | 0.84 | CAMKK2 (0.40) | LRRK2 | |
| SCHEMBL28828641 | 0.84 | PPIB (0.40) | — | |
| SCHEMBL28828448 | 0.83 | KDM6B (0.38) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |