Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828645 | 0.89 | AKR1C3 (0.38) | AKR1C3AKR1C2 | |
| SCHEMBL28950175 | 0.88 | F2R (0.37) | KDM1AKDM1B | |
| SCHEMBL28828460 | 0.87 | AKR1C3 (0.37) | AKR1C3AKR1C2RXRARXRBPTPN5 | |
| SCHEMBL28828619 | 0.85 | RXRA (0.43) | RXRARXRBACHE | |
| SCHEMBL28828502 | 0.85 | RXRA (0.34) | AKR1C3AKR1C2RXRARXRBKDM1A | |
| SCHEMBL29121190 | 0.85 | RXRA (0.34) | AKR1C3AKR1C2RXRARXRBKDM1A | |
| SCHEMBL29121273 | 0.85 | KDM1A (0.50) | AKR1C3AKR1C2KDM1AKDM1B | |
| SCHEMBL28828694 | 0.85 | KDM1A (0.50) | AKR1C3AKR1C2KDM1AKDM1B | |
| SCHEMBL28828651 | 0.84 | BCL2 (0.34) | KDM1AKDM1B | |
| SCHEMBL29121248 | 0.84 | BCL2 (0.34) | KDM1AKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |