Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828403 | 0.89 | AKR1C3 (0.34) | AKR1C3AKR1C2 | |
| SCHEMBL29121202 | 0.88 | APP (0.33) | SLC6A2SLC6A4SLC6A3APPCYP3A4 | |
| SCHEMBL28828683 | 0.86 | DHODH (0.38) | AKR1C3AKR1C2KIF11 | |
| SCHEMBL28828510 | 0.86 | PRKAB2 (0.39) | SLC6A2SLC6A4SLC6A3APPCYP3A4 | |
| SCHEMBL29121219 | 0.86 | PRKAB2 (0.39) | SLC6A2SLC6A4SLC6A3APPCYP3A4 | |
| SCHEMBL28828612 | 0.85 | APP (0.37) | AKR1C3AKR1C2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29121290 | 0.85 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3APPCYP3A4 | |
| SCHEMBL29121237 | 0.85 | APP (0.37) | AKR1C3AKR1C2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28828639 | 0.85 | CYP3A4 (0.41) | SLC6A2SLC6A4SLC6A3APPCYP3A4 | |
| SCHEMBL28828633 | 0.85 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3APPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |