Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121219 | 0.90 | PRKAB2 (0.39) | KDM1AKDM1BGRM2FFAR1 | |
| SCHEMBL28828510 | 0.90 | PRKAB2 (0.39) | KDM1AKDM1BGRM2FFAR1 | |
| SCHEMBL28828694 | 0.89 | KDM1A (0.50) | AKR1C3AKR1C2KDM1AKDM1BFFAR1 | |
| SCHEMBL29121273 | 0.89 | KDM1A (0.50) | AKR1C3AKR1C2KDM1AKDM1BFFAR1 | |
| SCHEMBL28828637 | 0.88 | STS (0.32) | — | |
| SCHEMBL27212738 | 0.87 | FFAR4 (0.32) | — | |
| SCHEMBL29121188 | 0.87 | FFAR4 (0.32) | — | |
| SCHEMBL29121222 | 0.86 | GRM2 (0.41) | KDM1AKDM1BGRM2FFAR1 | |
| SCHEMBL28828605 | 0.86 | GRM2 (0.41) | KDM1AKDM1BGRM2FFAR1 | |
| SCHEMBL28828414 | 0.85 | PTGS2 (0.39) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |