SCHEMBL4644189

SCHEMBL4644189

C=C(C)C(=O)OCCOCC1(CC)COC1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.54
TSHR P16473 6/20 0.41
ALDH1A1 P00352 2/20 0.37
POLB P06746 2/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14505099 0.99 THRB (0.53) THRBTSHRALDH1A1POLBHSD17B10
SCHEMBL10100417 0.94 THRB (0.51) THRBTSHRALDH1A1CA1CA2
SCHEMBL26703794 0.92 TSHR (0.50) THRBTSHRALDH1A1POLBHSD17B10
SCHEMBL4644865 0.92 TSHR (0.46) THRBTSHRALDH1A1POLBHSD17B10
SCHEMBL19856425 0.87 THRB (0.40) THRBTSHRALDH1A1POLBHSD17B10
SCHEMBL156498 0.86 ALDH1A1 (0.42) THRBTSHRALDH1A1POLBHSD17B10
SCHEMBL17123534 0.84 TSHR (0.48) THRBTSHRALDH1A1POLBHSD17B10
SCHEMBL244964 0.83 THRB (0.46) THRBTSHRALDH1A1POLBCA1
SCHEMBL21385260 0.83 THRB (0.37) THRBTSHRALDH1A1MEN1KMT2A
SCHEMBL12099746 0.82 THRB (0.53) THRBTSHRALDH1A1POLBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240180788-A1 PHOTOCATIONICALLY CURABLE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2024-06-06 US disclosed
EP-4310128-A1 PHOTOCATIONICALLY CURABLE COMPOSITION Tokuyama Dental Corporation (JP) 2024-01-24 EP disclosed
US-20230350294-A1 Negative Photosensitive Resin Composition, Patterning Process, Interlayer Insulating Film, Surface Protection Film, And Electronic Component SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-02 US disclosed
CN-111936524-B Photochromic curable composition 株式会社德山 2022-09-23 CN disclosed
CN-111936524-A Photochromic curable composition 株式会社德山 2020-11-13 CN disclosed
US-8735462-B2 Radical-polymerizable resin, radical-polymerizable resin composition, and cured material thereof DAICEL CORPORATION (JP) 2014-05-27 US disclosed
US-20130030078-A1 RADICAL-POLYMERIZABLE RESIN, RADICAL-POLYMERIZABLE RESIN COMPOSITION, AND CURED MATERIAL THEREOF DAICEL CORPORATION (JP) 2013-01-31 US disclosed
EP-1591098-B1 Cationically curable composition for dental use TOKUYAMA CORP (JP) 2008-08-13 EP disclosed
US-7365106-B2 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2008-04-29 US disclosed
US-7220530-B2 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-05-22 US disclosed
US-7220530-B2 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-05-22 US disclosed
US-20050250868-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-10 US disclosed
EP-1591098-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240180788-A1 PHOTOCATIONICALLY CURABLE COMPOSITION CRY1, CRY2, TYR THRB 4645/4885TSHR 4550/4885ALDH1A1 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.