Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.32 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.32 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.32 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.32 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.32 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121316 | 0.91 | EPHX1 (0.36) | PTGS2MMP2MMP9 | |
| SCHEMBL28828404 | 0.91 | EPHX1 (0.36) | PTGS2MMP2MMP9 | |
| SCHEMBL29121256 | 0.90 | GRIA2 (0.34) | F10PRSS1F2GRIA2PTGS2 | |
| SCHEMBL29121243 | 0.88 | BCL2 (0.43) | F10PRSS1F2GRIA2PTGS2 | |
| SCHEMBL28828387 | 0.88 | BCL2 (0.43) | F10PRSS1F2GRIA2PTGS2 | |
| SCHEMBL28828659 | 0.86 | PLA2G10 (0.33) | PTGS2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL29121158 | 0.86 | PLA2G10 (0.33) | PTGS2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL28828535 | 0.85 | HTR7 (0.34) | F10PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL29121307 | 0.84 | RXRA (0.44) | MMP2MMP9 | |
| SCHEMBL28828501 | 0.84 | RXRA (0.44) | MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |