Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.33 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.33 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.33 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.33 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.33 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828644 | 0.90 | EPHX1 (0.35) | LDHA | |
| SCHEMBL28828531 | 0.90 | LMNA (0.36) | HTR7PLA2G2ACTSAFFAR1PDE4D | |
| SCHEMBL29121158 | 0.88 | PLA2G10 (0.33) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL28828659 | 0.88 | PLA2G10 (0.33) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL28828451 | 0.87 | CTSA (0.38) | AKR1C3AKR1C2CTSAMTNR1B | |
| SCHEMBL28828597 | 0.85 | PRMT5 (0.37) | CTSAFFAR1 | |
| SCHEMBL28828650 | 0.85 | F10 (0.35) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL28828663 | 0.85 | RXRA (0.36) | AKR1C3AKR1C2 | |
| SCHEMBL28828506 | 0.84 | CYP1A1 (0.40) | — | |
| SCHEMBL28828464 | 0.84 | F2R (0.39) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |