Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049177 | 0.83 | MAPT (0.49) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL3436409 | 0.82 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL10517126 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL3107758 | 0.72 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL3436395 | 0.71 | ALOX5 (0.51) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL3973924 | 0.70 | ALDH1A1 (0.69) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL10049173 | 0.68 | AOC3 (0.66) | ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5842967 | 0.67 | ALDH1A1 (1.00) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL28665194 | 0.67 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10KDM4ETDP1 | |
| SCHEMBL3362186 | 0.67 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985405-B | Heterocyclic compounds and p27Kip1Decomposition inhibitor | ASKA制药株式会社 | 2016-07-06 | — | — | CN | disclosed |