SCHEMBL3436409

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10517126	0.88	ALDH1A1 (0.52)	ALDH1A1HSD17B10KDM4ENPC1RAB9A
	SCHEMBL3107758	0.87	ALDH1A1 (0.51)	ALDH1A1HSD17B10KDM4ENPC1RAB9A
	SCHEMBL3436395	0.83	ALOX5 (0.51)	ALDH1A1HSD17B10KDM4ENPC1RAB9A
	SCHEMBL28828771	0.82	ALDH1A1 (0.48)	ALDH1A1HSD17B10KDM4ENPC1RAB9A
	SCHEMBL27658248	0.79	ALDH1A1 (0.61)	ALDH1A1HSD17B10KDM4ENPC1RAB9A
	SCHEMBL28665194	0.79	ALDH1A1 (0.52)	ALDH1A1HSD17B10KDM4ENPC1RAB9A
	SCHEMBL3362186	0.78	ALDH1A1 (0.50)	ALDH1A1HSD17B10KDM4ENPC1RAB9A
	SCHEMBL557753	0.76	NPC1 (0.73)	ALDH1A1HSD17B10KDM4ENPC1RAB9A
	SCHEMBL3106748	0.76	ERN1 (0.51)	ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD
	SCHEMBL5842967	0.75	ALDH1A1 (1.00)	ALDH1A1HSD17B10KDM4EHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.