Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 18/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 18/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828981 | 1.00 | AVPR2 (0.41) | AVPR2AVPR1AALDH1A1HPGDMAPT | |
| SCHEMBL29810760 | 0.87 | AVPR2 (0.39) | AVPR2AVPR1A | |
| SCHEMBL28829027 | 0.81 | ALDH1A1 (0.42) | AVPR2AVPR1AALDH1A1HPGDMAPT | |
| SCHEMBL28828769 | 0.76 | AVPR2 (0.42) | AVPR2AVPR1A | |
| SCHEMBL28828770 | 0.76 | AVPR2 (0.42) | AVPR2AVPR1A | |
| SCHEMBL11258178 | 0.76 | APEX1 (0.52) | ALDH1A1HPGDMAPTNPSR1RXFP1 | |
| SCHEMBL409762 | 0.75 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL256612 | 0.75 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL460084 | 0.75 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL28829068 | 0.74 | AVPR2 (0.41) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835688-A | Substituted 4-aryl imidazole-2-ketone derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-02 | — | — | CN | disclosed |