Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.47 |
| ▸ | MME | P08473 | 5/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934656 | 0.81 | TGFBR1 (0.52) | TGFBR1MMESLC7A5FOLH1NAALAD2 | |
| SCHEMBL28581576 | 0.81 | TGFBR1 (0.52) | TGFBR1MMESLC7A5FOLH1NAALAD2 | |
| SCHEMBL16750049 | 0.76 | TGFBR1 (0.50) | TGFBR1MMEOR51E2FOLH1NAALAD2 | |
| SCHEMBL9911356 | 0.76 | TGFBR1 (0.50) | TGFBR1MMEOR51E2FOLH1NAALAD2 | |
| SCHEMBL16750052 | 0.76 | TGFBR1 (0.50) | TGFBR1MMEOR51E2FOLH1NAALAD2 | |
| SCHEMBL8575470 | 0.75 | TGFBR1 (0.58) | TGFBR1MMEOR51E2FOLH1NAALAD2 | |
| SCHEMBL1251586 | 0.73 | TGFBR1 (0.48) | TGFBR1MMEUSP2 | |
| SCHEMBL29449289 | 0.73 | MME (0.50) | TGFBR1MMEPDCD1LG2CD274 | |
| SCHEMBL29375393 | 0.73 | MME (0.50) | TGFBR1MMEPDCD1LG2CD274 | |
| SCHEMBL22731504 | 0.72 | TGFBR1 (0.47) | TGFBR1MMEOR51E2FOLH1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111100086-B | 1,3, 4-oxadiazole-2-cyclobutyl compound and preparation method thereof | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |