SCHEMBL29375393

SCHEMBL29375393

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nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.50
TGFBR1 P36897 3/20 0.48
CTSC P53634 1/20 0.48
ACE P12821 1/20 0.42
PDCD1LG2 Q9BQ51 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
TARS1 P26639 1/20 0.38
ECE1 P42892 1/20 0.38
CA2 P00918 2/20 0.37
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29449289 1.00 MME (0.50) MMETGFBR1CTSCACEPDCD1LG2
SCHEMBL29746975 0.96 MME (0.47) MMETGFBR1CTSCACEPDCD1LG2
SCHEMBL29849851 0.93 MME (0.45) MMETGFBR1CTSCACEPDCD1LG2
SCHEMBL31696976 0.92 MME (0.44) MMETGFBR1CTSCACEPDCD1LG2
SCHEMBL30406096 0.91 MME (0.54) MMETGFBR1CTSC
SCHEMBL30011153 0.89 MME (0.42) MMETGFBR1CTSCPDCD1LG2CD274
SCHEMBL30340139 0.89 PDCD1LG2 (0.51) MMETGFBR1CTSCPDCD1LG2CD274
SCHEMBL30906339 0.88 MME (0.41) MMETGFBR1CTSCPDCD1LG2CD274
Trifluoroacetic Acid SCHEMBL4092935 0.88 MME (0.41) MMETGFBR1CTSCACEPDCD1LG2
SCHEMBL29564528 0.87 ACE (0.54) MMETGFBR1CTSCACEPDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171776-A1 NON-CANONICAL CELL-PENETRATING PEPTIDES FOR ANTISENSE OLIGOMER DELIVERY SAREPTA THERAPEUTICS, INC. (US) 2025-05-29 US claimed
US-20250145828-A1 TRANSPARENT PROTEIN MATERIALS TANDEM REPEAT TECHNOLOGIES, INC. 2025-05-08 US claimed
CN-114190531-B Preparation of mackerel flavor peptide and preparation method and application thereof 浙江万里学院 2023-12-12 CN claimed
CN-116769860-A Enzymatic hydrolysis of crayfish shells, oligopeptide family extracted from crayfish shells and application of crayfish shells 奇明达(北京)植物药物技术开发有限公司 2023-09-19 CN claimed
WO-2023158960-A2 TRANSPARENT PROTEIN MATERIALS TANDEM REPEAT TECHNOLOGIES, INC. (US) 2023-08-24 WO claimed
EP-4107183-A1 ANTI-CD19/ANTI-CD3 BISPECIFIC ANTIBODY, T CELLS SECRETING THE SAME, METHOD OF PREPARATION AND USE THEREOF Fundación para la Investigación Biomédica del Hospital Universitario 12 de Octubre (ES) 2022-12-28 EP claimed
US-11518794-B2 Synthesis method for liraglutide with low racemate impurity Shenzhen JYMed Technology Co., Ltd. (CN) 2022-12-06 US claimed
US-12559564-B2 Compositions and methods for preventing or reversing t-cell exhaustion through ectonucleotidase inhibition and antibody-mediated target cytosis BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2026-02-24 US disclosed
EP-3509604-B1 COMBINATION THERAPIES USING IMMUNO-DASH INHIBITORS AND PGE2 ANTAGONISTS TUFTS COLLEGE (US) 2026-02-18 EP disclosed
US-20260036547-A1 METHODS FOR DETECTING METABOLITES USING A MICROFLUIDIC-BASED CE-MS SYSTEM ASTRAZENECA AB (SE) 2026-02-05 US disclosed
EP-4680631-A1 COMBOTOPE ANTIBODY LIBRARIES Danmarks Tekniske Universitet (DK) 2026-01-21 EP disclosed
US-12478609-B2 Combination therapies using immuno-DASH inhibitors and PGE2 antagonists TRUSTEES OF TUFTS COLLEGE (US) 2025-11-25 US disclosed
US-20250345411-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2025-11-13 US disclosed
CN-112521471-B Gene and molecular marker for controlling water content of corn kernels and application thereof 华中农业大学 2022-04-05 CN disclosed
WO-2022056200-A1 METHODS AND COMPOSITIONS FOR POTENTIATING ANTITUMORAL IMMUNE RESPONSES THROUGH TARGETING OF NTPDASE3 Purinomia Biotech, Inc. (US) 2022-03-17 WO disclosed
US-20220062375-A1 Compositions and Methods for Dengue Virus Chimeric Constructions in Vaccines TAKEDA VACCINES, INC. (US) 2022-03-03 US disclosed
CN-114127121-A Methods and compositions for promoting and enhancing T cell-mediated immune responses by ADCC targeting of CD39 expressing cells 北京恩瑞尼生物科技股份有限公司 2022-03-01 CN disclosed
US-11248034-B2 Insulin analogs UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2022-02-15 US disclosed
US-20220040149-A1 COMBINATION THERAPIES USING IMMUNO-DASH INHIBITORS AND PGE2 ANTAGONISTS TRUSTEES OF TUFTS COLLEGE 2022-02-10 US disclosed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12478609-B2 Combination therapies using immuno-DASH inhibitors and PGE2 antagonists HPGDS, PTGIS, PTGDR2 MME 887/4885TGFBR1 2372/4885CTSC 1051/4885
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP MME 1189/4885TGFBR1 2486/4885CTSC 26/4885
US-12559564-B2 Compositions and methods for preventing or reversing t-cell exhaustion through ectonucleotidase inhibition and antibody-mediated target cytosis ENTPD1, FCGR2A, FCGR1A MME 560/4885TGFBR1 708/4885CTSC 852/4885
US-20220040149-A1 COMBINATION THERAPIES USING IMMUNO-DASH INHIBITORS AND PGE2 ANTAGONISTS HPGDS, PTGIS, PTGDR2 MME 887/4885TGFBR1 2372/4885CTSC 1051/4885
US-20250171776-A1 NON-CANONICAL CELL-PENETRATING PEPTIDES FOR ANTISENSE OLIGOMER DELIVERY MYOF, TNNC1, MTPN MME 455/4885TGFBR1 3013/4885CTSC 643/4885
US-20260036547-A1 METHODS FOR DETECTING METABOLITES USING A MICROFLUIDIC-BASED CE-MS SYSTEM ATP5ME, ATP5MF, ATP5MK MME 298/4885TGFBR1 3678/4885CTSC 746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.