Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857505 | 0.84 | RIPK1 (0.51) | CTSKCTSSRIPK1BCAT2MAPT | |
| SCHEMBL5654433 | 0.84 | RIPK1 (0.51) | CTSKCTSSRIPK1BCAT2MAPT | |
| SCHEMBL5694863 | 0.80 | CTSK (0.47) | CTSKCTSSRIPK1BCAT2MAPT | |
| SCHEMBL9420598 | 0.78 | RIPK1 (0.46) | CTSKCTSSRIPK1BCAT2MAPT | |
| SCHEMBL18921533 | 0.78 | RIPK1 (0.50) | CTSKCTSSRIPK1BCAT2MAPT | |
| SCHEMBL22456387 | 0.78 | RIPK1 (0.50) | CTSKCTSSRIPK1BCAT2MAPT | |
| SCHEMBL22232743 | 0.78 | RIPK1 (0.50) | CTSKCTSSRIPK1BCAT2MAPT | |
| SCHEMBL1948655 | 0.77 | CA12 (0.50) | CTSKCTSSPPARGPPARACA12 | |
| SCHEMBL350453 | 0.77 | NPC1 (0.58) | CTSKCTSSRIPK1BCAT2ATM | |
| SCHEMBL1624911 | 0.77 | NPC1 (0.58) | CTSKCTSSRIPK1BCAT2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867630-A | - 1 receptor modulators of novel glp-1 | 赛尔基因第二国际有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-105593225-B | novel GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-105593225-A | Novel GLP-1 receptor modulators | RECEPTOS INC | 2016-05-18 | — | — | CN | disclosed |