Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857505 | 1.00 | RIPK1 (0.51) | RIPK1LMNACTSSCTSKBCAT2 | |
| SCHEMBL9420598 | 0.87 | RIPK1 (0.46) | RIPK1LMNACTSSCTSKBCAT2 | |
| SCHEMBL6545363 | 0.87 | RIPK1 (0.46) | RIPK1LMNACTSSCTSKBCAT2 | |
| SCHEMBL28829142 | 0.84 | CTSK (0.45) | RIPK1CTSSCTSKBCAT2MAPT | |
| SCHEMBL28022209 | 0.83 | RIPK1 (0.57) | RIPK1LMNACTSSCTSKBCAT2 | |
| SCHEMBL8770937 | 0.83 | AOC3 (0.42) | CTSSCTSKMAPTCYP2D6ALDH1A1 | |
| SCHEMBL8770922 | 0.83 | AOC3 (0.42) | LMNACYP2D6TSHRAOC3 | |
| SCHEMBL5922341 | 0.83 | FFAR1 (0.40) | LMNASMN1; SMN2CYP2D6ALDH1A1TSHR | |
| SCHEMBL8770939 | 0.83 | NPC1 (0.39) | CTSSCTSKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8770928 | 0.83 | FFAR1 (0.51) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102851101-B | Lubricant additive and preparation method thereof | BAIYIN XINSHENG CHEMICAL NEW MATERIAL TECHNOLOGY CO LTD | 2013-12-18 | — | — | CN | claimed |
| CN-102851101-A | Lubricant additive and preparation method thereof | BAIYIN XINSHENG CHEMICAL NEW MATERIAL TECHNOLOGY CO LTD | 2013-01-02 | — | — | CN | claimed |
| CN-102851101-B | Lubricant additive and preparation method thereof | BAIYIN XINSHENG CHEMICAL NEW MATERIAL TECHNOLOGY CO LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-102851101-A | Lubricant additive and preparation method thereof | BAIYIN XINSHENG CHEMICAL NEW MATERIAL TECHNOLOGY CO LTD | 2013-01-02 | — | — | CN | disclosed |
| US-20070292540-A1 | Extracts and Methods Comprising Cinnamon Species | HERBALSCIENCE SINGAPORE PTE. LTD. (SG) | 2007-12-20 | — | — | US | disclosed |
| US-6911468-B2 | Tyrosine phosphatase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| EP-1319664-B1 | Process for the preparation of organozinc halogen compounds from reactive halogen compounds and use thereof | CONSORTIUM ELEKTROCHEM IND (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6603034-B2 | Reacting a reactive halogen compound with zinc in one or more carboxylic esters. It is also possible to prepare keto, hydroxyl and amino compounds of organozinc halides obtained in a first step from a reactive halogen compound and zinc in one | Consortium für elektrochemische Industrie GmbH (DE) | 2003-08-05 | — | — | US | disclosed |
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |
| US-20030114697-A1 | PREPARATION OF ORGANOZINC HALIDES FROM REACTIVE HALOGEN COMPOUNDS AND THEIR USE | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2003-06-19 | — | — | US | disclosed |
| EP-1319664-A1 | Process for the preparation of organozinc halogen compounds from reactive halogen compounds and use thereof | Consortium für elektrochemische Industrie GmbH (DE) | 2003-06-18 | — | — | EP | disclosed |
| EP-1284260-A1 | TYROSINE PHOSPHATASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | PTPRC, PTPN1, PTPRM | RIPK1 974/4885LMNA 4447/4885CTSS 3395/4885 |
| US-20070292540-A1 | Extracts and Methods Comprising Cinnamon Species | MT-CO2, CA7, CES2 | RIPK1 3378/4885LMNA 1528/4885CTSS 976/4885 |
| US-20030114697-A1 | PREPARATION OF ORGANOZINC HALIDES FROM REACTIVE HALOGEN COMPOUNDS AND THEIR USE | ZRANB2, ZKSCAN2, ZCCHC8 | RIPK1 3655/4885LMNA 4330/4885CTSS 1764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.