SCHEMBL28829172

SCHEMBL28829172

O=C(O)c1ccc(OCC2CCCN2Cc2ccccc2)cc1CCl

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FAAH O00519 13/20 0.61
SPHK1 Q9NYA1 5/20 0.50
SPHK2 Q9NRA0 4/20 0.50
LTA4H P09960 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23546075 0.88 FAAH (0.56) FAAHSPHK1SPHK2
SCHEMBL30069125 0.88 FAAH (0.56) FAAHSPHK1SPHK2
Oxalic Acid SCHEMBL9683845 0.74 FAAH (0.57) FAAHSPHK1SPHK2LTA4H
SCHEMBL23533223 0.73 LTA4H (0.44) FAAHLTA4H
SCHEMBL23532997 0.73 FAAH (0.64) FAAHSPHK1SPHK2
SCHEMBL23533000 0.73 FAAH (0.64) FAAHSPHK1SPHK2
SCHEMBL12987302 0.72 FAAH (0.49) FAAHSPHK1SPHK2
SCHEMBL12987301 0.72 FAAH (0.49) FAAHSPHK1SPHK2
SCHEMBL7297678 0.72 FAAH (0.60) FAAHSPHK1SPHK2LTA4H
SCHEMBL29046164 0.71 FAAH (0.51) FAAHSPHK1SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114828959-B 3- (5-methoxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivative and application thereof 诺华股份有限公司 2024-04-02 CN disclosed
CN-114828959-A 3- (5-methoxy-1-oxoisoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof 诺华股份有限公司 2022-07-29 CN disclosed