Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136039 | 0.88 | ACP3 (0.44) | MEN1KMT2AACP3DPP4DPP7 | |
| SCHEMBL22895027 | 0.82 | GRN (0.49) | MEN1KMT2APPARGPPARAALDH1A1 | |
| SCHEMBL8194317 | 0.82 | MEN1 (0.42) | MEN1KMT2AACP3PPARGKEAP1 | |
| SCHEMBL3954719 | 0.81 | MEN1 (0.47) | MEN1KMT2AACP3KEAP1NFE2L2 | |
| SCHEMBL28789627 | 0.81 | HDAC4 (0.49) | — | |
| SCHEMBL3435446 | 0.79 | PTPN5 (0.46) | — | |
| SCHEMBL5574337 | 0.79 | CES2 (0.54) | MEN1KMT2AACP3PPARGPPARA | |
| SCHEMBL195532 | 0.79 | SRC (0.50) | ACP3 | |
| SCHEMBL7955519 | 0.79 | SRC (0.50) | ACP3 | |
| SCHEMBL4026079 | 0.79 | SRC (0.50) | ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103687860-B | As P2X7Heterocyclic amide derivatives of receptor antagonists | 埃科特莱茵药品有限公司 | 2016-06-08 | — | — | CN | disclosed |