Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL28160737 | 0.86 | MAPT (0.63) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL631962 | 0.86 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNATSHRAKR1C3 | |
| Carbamic Acid SCHEMBL27930251 | 0.84 | NPC1 (0.61) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL5492248 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNATSHRAKR1C3 | |
| Acetic Acid SCHEMBL27760577 | 0.84 | MAPT (0.61) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| Urea SCHEMBL27797099 | 0.84 | NPC1 (0.61) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL1968506 | 0.83 | L3MBTL1 (0.59) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL2312380 | 0.83 | L3MBTL1 (0.59) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL93630 | 0.83 | L3MBTL1 (0.59) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL8542780 | 0.83 | L3MBTL1 (0.59) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636963-B | For synthesizing the method for Irinotecan | 赛比亚斯药业股份公司 | 2018-07-03 | — | — | CN | disclosed |
| CN-105636963-A | Method for the synthesis of irinotecan | SYNBIAS PHARMA AG | 2016-06-01 | — | — | CN | disclosed |