Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829531 | 0.81 | CYP3A4 (0.41) | LMNAGAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL14042913 | 0.79 | KDM4E (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28018573 | 0.75 | KDM4E (0.52) | KDM4ELMNAALOX12GAAMAPT | |
| SCHEMBL729159 | 0.73 | ATR (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28060869 | 0.73 | PDK1 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5361399 | 0.73 | CA12 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24926410 | 0.67 | ELANE (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28370638 | 0.67 | ELANE (0.62) | ELANELMNAMAPTNPSR1 | |
| SCHEMBL364665 | 0.67 | ELANE (0.53) | ELANELMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL31031255 | 0.67 | ELANE (0.53) | ELANELMNAMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214482-B | Imidazo [1,2-a] pyridine compounds as receptor tyrosine kinase inhibitors | 阵列生物制药公司 | 2016-06-29 | — | — | CN | disclosed |