Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL17220640 | 0.91 | TP53 (0.44) | TP53PLA2G1BPLA2G2A | |
| Diethylamine SCHEMBL28081053 | 0.86 | — | — | |
| Diethylamine SCHEMBL9164426 | 0.80 | TP53 (0.50) | TP53 | |
| Diethylamine SCHEMBL28275121 | 0.79 | PLA2G1B (0.32) | TP53PLA2G1BPLA2G2A | |
| Propylamine SCHEMBL1760597 | 0.77 | DNM1 (0.37) | PLA2G1BPLA2G2A | |
| Diethylamine SCHEMBL80173 | 0.77 | — | — | |
| Diethylamine SCHEMBL1806685 | 0.77 | TP53 (0.61) | TP53 | |
| Diethylamine SCHEMBL7543246 | 0.77 | — | — | |
| Isopropylamine SCHEMBL4924220 | 0.77 | PLA2G1B (0.39) | PLA2G1BPLA2G2A | |
| Diethylamine SCHEMBL11359408 | 0.74 | TP53 (0.57) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793363-A | Conductive compositions and layers made therefrom | 索尔维公司 | 2016-07-20 | — | — | CN | disclosed |