SCHEMBL28829904

SCHEMBL28829904

COc1ccc(CC2CC2(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
IDO1 P14902 2/20 0.45
TLR9 Q9NR96 1/20 0.43
AGXT P21549 1/20 0.42
LTA4H P09960 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27655946 0.75 GLA (0.49) GLANPSR1IDO1TLR9
SCHEMBL622656 0.74 IDO1 (0.50) IDO1CA12CA1CA2CA7
SCHEMBL33373858 0.73 GLA (0.46) GLANPSR1IDO1TLR9AGXT
Ammonia Solution, Strong SCHEMBL8172708 0.72 IDO1 (0.48) IDO1
SCHEMBL3367622 0.71 LTA4H (0.48) IDO1LTA4H
SCHEMBL21678055 0.71 CYP2D6 (0.49) IDO1CA12CA1CA2CA7
SCHEMBL28335303 0.71 PKM (0.49) GLANPSR1IDO1TLR9AGXT
SCHEMBL4821864 0.71 PKM (0.49) GLANPSR1IDO1TLR9AGXT
SCHEMBL3365060 0.71 LTA4H (0.51) IDO1LTA4H
SCHEMBL13970345 0.71 IDO1 (0.47) IDO1AGXTLTA4HTAAR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003110-B Aryl beta-aminoketone compound and preparation method thereof 南京工业大学 2022-09-06 CN claimed