SCHEMBL622656

SCHEMBL622656

COc1ccc(CC2CC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.50
CYP26A1 O43174 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL8172708 0.98 IDO1 (0.48) IDO1CYP26A1MEN1KMT2ASMN1; SMN2
SCHEMBL13504115 0.92 OPRK1 (0.51)
SCHEMBL3365060 0.92 LTA4H (0.51) IDO1
SCHEMBL3367622 0.92 LTA4H (0.48) IDO1
SCHEMBL11465115 0.91 CYP26A1 (0.43) IDO1CYP26A1MEN1KMT2ASMN1; SMN2
SCHEMBL5527859 0.91 TAAR1 (0.48) IDO1
SCHEMBL5527855 0.91 TAAR1 (0.48) IDO1
SCHEMBL5516474 0.91 CYP26A1 (0.47) CYP26A1MEN1KMT2ASMN1; SMN2
SCHEMBL22023702 0.91 HRH3 (0.52) CYP26A1MEN1KMT2ASMN1; SMN2
SCHEMBL4349439 0.91 KDM1A (0.44) IDO1CYP26A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559703-B2 Fragrance composition GIVAUDAN SA (CH) 2026-02-24 US claimed
EP-4655373-A1 BIODEGRADABLE PERFUME COMPOSITION Givaudan SA (CH) 2025-12-03 EP claimed
WO-2025202258-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2025-10-02 WO claimed
EP-4532646-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-04-09 EP claimed
CN-119317696-A Perfume mixture (V) 西姆莱斯股份公司 2025-01-14 CN claimed
US-20240301331-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-09-12 US claimed
WO-2024156688-A1 BIODEGRADABLE PERFUME COMPOSITION GIVAUDAN SA (CH) 2024-08-02 WO claimed
EP-4407019-A1 BIODEGRADABLE PERFUME COMPOSITION Givaudan SA (CH) 2024-07-31 EP claimed
US-20240225971-A1 1,3-BUTYLENE GLYCOL COMPOSITIONS AND METHODS OF USE THEREOF AGAIN BIO APS (DK) 2024-07-11 US claimed
EP-4294906-A1 IMPROVEMENT IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2023-12-27 EP claimed
US-20080247966-A1 Compositions and Methods to Counteract Oral Malodour GIVAUDAN SA (CH) 2008-10-09 US claimed
EP-1968531-A2 TOPICAL COMPOSITIONS FOR REDUCING SKIN IRRITATION Givaudan SA (CH) 2008-09-17 EP claimed
CN-101262843-A Improvements in or related to organic compounds GIVAUDAN SA (CH) 2008-09-10 CN claimed
EP-1919566-A1 COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR Givaudan SA (CH) 2008-05-14 EP claimed
WO-2007030961-A2 TOPICAL COMPOSITIONS FOR REDUCING SKIN IRRITATION GIVAUDAN SA (CH) 2007-03-22 WO claimed
WO-2007025401-A1 COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR GIVAUDAN SA (CH) 2007-03-08 WO claimed
US-20050042255-A1 Fragrance and flavour compositions GIVAUDAN SA (CH) 2005-02-24 US claimed
EP-1401388-A2 FRAGRANCE AND FLAVOUR COMPOSITIONS Givaudan SA (CH) 2004-03-31 EP claimed
WO-2003002084-A2 FRAGRANCE AND FLAVOUR COMPOSITIONS GIVAUDAN SA (CH) 2003-01-09 WO claimed
EP-1269982-A1 Fragrance and flavour compositions Givaudan SA (CH) 2003-01-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559703-B2 Fragrance composition DHCR24, OPRD1, OR10J3 IDO1 1640/4885CYP26A1 331/4885CA12 2491/4885
US-20050042255-A1 Fragrance and flavour compositions C5, FAAH2, TRPA1 IDO1 1241/4885CYP26A1 327/4885CA12 3520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.