Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.98 |
| ▸ | NPC1 | O15118 | 8/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.98 |
| ▸ | MEN1 | O00255 | 7/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.98 |
| ▸ | HTT | P42858 | 4/20 | 0.98 |
| ▸ | CASP1 | P29466 | 3/20 | 0.98 |
| ▸ | CASP7 | P55210 | 3/20 | 0.98 |
| ▸ | ATM | Q13315 | 3/20 | 0.98 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.98 |
| ▸ | HBB | P68871 | 2/20 | 0.98 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.98 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.98 |
| ▸ | TSHR | P16473 | 1/20 | 0.98 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.98 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.98 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357085 | 0.99 | MAPT (1.00) | MAPTNPC1KDM4EKMT2AMEN1 | |
| SCHEMBL457303 | 0.99 | MAPT (1.00) | MAPTNPC1KDM4EKMT2AMEN1 | |
| SCHEMBL29582969 | 0.98 | MAPT (0.98) | MAPTNPC1KDM4EKMT2AMEN1 | |
| SCHEMBL30874254 | 0.91 | MAPT (0.85) | MAPTNPC1KDM4EKMT2AMEN1 | |
| SCHEMBL24220026 | 0.91 | MAPT (0.85) | MAPTNPC1KDM4EKMT2AMEN1 | |
| SCHEMBL21753748 | 0.90 | NPC1 (0.82) | MAPTNPC1KDM4EKMT2AMEN1 | |
| SCHEMBL26493464 | 0.89 | MAPT (0.81) | MAPTNPC1KDM4EKMT2AMEN1 | |
| SCHEMBL2202346 | 0.88 | MAPT (0.79) | MAPTNPC1KDM4EKMT2AMEN1 | |
| SCHEMBL23450211 | 0.88 | MAPT (0.79) | MAPTNPC1KDM4EKMT2AMEN1 | |
| SCHEMBL4506209 | 0.87 | NPC1 (0.78) | MAPTNPC1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915957-A | Compositions and methods for modulating mRNA splicing | 恩特拉达治疗学股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117897176-A | Compositions and methods for modulating tissue distribution of intracellular therapeutic agents | 恩特拉达治疗学股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117561271-A | Cyclic cell penetrating peptides | 恩特拉达治疗公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-114981205-A | Pristine graphene-based biosensors for biomarker detection and related core particles, material composition methods and systems | 鹰眼生物有限公司 | 2022-08-30 | — | — | CN | disclosed |