SCHEMBL24220026

SCHEMBL24220026

CCN(CC)c1ccc2cc3cc(-c4nc5ccccc5n4C)c(=O)oc3cc2c1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 0.85
▸ KMT2A Q03164 9/20 0.85
▸ NPC1 O15118 8/20 0.85
▸ KDM4E B2RXH2 8/20 0.85
▸ MEN1 O00255 8/20 0.85
▸ SMN1; SMN2 Q16637 6/20 0.85
▸ ALDH1A1 P00352 6/20 0.85
▸ HTT P42858 6/20 0.85
▸ CASP1 P29466 4/20 0.85
▸ CASP7 P55210 4/20 0.85
▸ ATM Q13315 4/20 0.85
▸ HSD17B10 Q99714 3/20 0.85
▸ HBB P68871 2/20 0.85
▸ NPSR1 Q6W5P4 2/20 0.85
▸ L3MBTL1 Q9Y468 2/20 0.85
▸ HCRTR1 O43613 1/20 0.85
▸ TSHR P16473 1/20 0.85
▸ TLR9 Q9NR96 1/20 0.85
▸ RAB9A P51151 7/20 0.61
▸ HPGD P15428 4/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30874254 1.00 MAPT (0.85) MAPTKMT2ANPC1KDM4EMEN1
SCHEMBL457303 0.92 MAPT (1.00) MAPTKMT2ANPC1KDM4EMEN1
SCHEMBL29357085 0.92 MAPT (1.00) MAPTKMT2ANPC1KDM4EMEN1
SCHEMBL28830001 0.91 MAPT (0.98) MAPTKMT2ANPC1KDM4EMEN1
SCHEMBL29582969 0.91 MAPT (0.98) MAPTKMT2ANPC1KDM4EMEN1
SCHEMBL21753748 0.83 NPC1 (0.82) MAPTKMT2ANPC1KDM4EMEN1
SCHEMBL26493464 0.82 MAPT (0.81) MAPTKMT2ANPC1KDM4EMEN1
SCHEMBL2202346 0.81 MAPT (0.79) MAPTKMT2ANPC1KDM4EMEN1
SCHEMBL23450211 0.81 MAPT (0.79) MAPTKMT2ANPC1KDM4EMEN1
SCHEMBL31022419 0.80 NPC1 (0.78) MAPTKMT2ANPC1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220163545-A1 REAGENT FOR FLUORESCENCE IMAGING OF LIPID DROPLETS IN CELL AND TISSUE NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) 2022-05-26 — — US disclosed
EP-3943919-A1 REAGENT FOR FLUORESCENCE IMAGING OF LIPID DROPLETS IN CELL AND TISSUE National University Corporation Gunma University (JP) 2022-01-26 — — EP disclosed
CN-113597547-A Fluorescent imaging agent for lipid droplets in cells and tissues 国立大学法人群马大学 2021-11-02 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220163545-A1 REAGENT FOR FLUORESCENCE IMAGING OF LIPID DROPLETS IN CELL AND TISSUE PLIN3, STARD7, PLIN5 MAPT 3031/4885KMT2A 3676/4885NPC1 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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