SCHEMBL28830304

SCHEMBL28830304

CC(C)(C[C@@H]1CNC(=O)C1)NC(=O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 1/20 0.32
SYK P43405 1/20 0.31
SSTR4 P31391 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28908986 1.00 FEN1 (0.32) FEN1SYKSSTR4
SCHEMBL19486191 0.77 SYK (0.34) FEN1SYK
SCHEMBL1673183 0.76 SYK (0.32) SYK
SCHEMBL5961468 0.74 CD274 (0.33) SYK
SCHEMBL28187856 0.72 SLC6A1 (0.50) SSTR4
SCHEMBL28469067 0.72 SLC6A1 (0.50) SSTR4
SCHEMBL19045190 0.72 PDE4A (0.33) SYK
SCHEMBL15564076 0.71 MTNR1A (0.41) FEN1SYK
SCHEMBL12069210 0.71 IRAK4 (0.34) SYK
SCHEMBL7550865 0.70 GABRA5 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114845711-A Inhibitors of RAF kinase 金耐特生物制药公司 2022-08-02 CN disclosed