Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051724 | 1.00 | L3MBTL1 (0.36) | L3MBTL1ALOX5RAB9ANPC1HTR6 | |
| SCHEMBL28830431 | 0.95 | L3MBTL1 (0.35) | L3MBTL1ALOX5RAB9ANPC1HTR6 | |
| SCHEMBL28830509 | 0.95 | L3MBTL1 (0.35) | L3MBTL1ALOX5RAB9ANPC1HTR6 | |
| SCHEMBL30052320 | 0.95 | L3MBTL1 (0.35) | L3MBTL1ALOX5RAB9ANPC1HTR6 | |
| SCHEMBL28950453 | 0.88 | ALDH1A1 (0.34) | L3MBTL1ALOX5RAB9AALDH1A1GAA | |
| SCHEMBL23119942 | 0.88 | L3MBTL1 (0.39) | L3MBTL1RAB9ANPC1HTR6CYP3A4 | |
| SCHEMBL29634651 | 0.87 | L3MBTL1 (0.35) | L3MBTL1RAB9AHTR6ACVR1CYP3A4 | |
| SCHEMBL30053626 | 0.86 | L3MBTL1 (0.38) | L3MBTL1RAB9AHTR6CYP3A4CYP2D6 | |
| SCHEMBL28830386 | 0.86 | L3MBTL1 (0.38) | L3MBTL1RAB9AHTR6CYP3A4CYP2D6 | |
| SCHEMBL30053498 | 0.86 | L3MBTL1 (0.32) | L3MBTL1ALOX5RAB9AACVR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724142-B | Amide or sulfonamide substituted hydrazine derivatives as JAK kinase inhibitors | 启元生物(杭州)有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-110724142-A | Amide or sulfonamide substituted hydrazine derivatives as JAK kinase inhibitors | 维眸生物科技（上海）有限公司 | 2020-01-24 | — | — | CN | disclosed |