Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364554 | 0.76 | CA2 (0.40) | SLC40A1 | |
| SCHEMBL13811756 | 0.75 | KDM4E (0.50) | KDM4EL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL29468592 | 0.74 | ALDH1A1 (0.55) | KDM4EL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL475089 | 0.74 | ALDH1A1 (0.55) | KDM4EL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL14491150 | 0.74 | HTR6 (0.50) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL6582497 | 0.72 | MAPT (0.43) | KDM4EL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL18184073 | 0.69 | — | — | |
| SCHEMBL2850037 | 0.68 | SMN1; SMN2 (0.33) | ALDH1A1HTTSMN1; SMN2GAALMNA | |
| SCHEMBL2657251 | 0.68 | ALDH1A1 (0.43) | KDM4EL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL1713160 | 0.67 | HTR6 (0.57) | KDM4EL3MBTL1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724142-B | Amide or sulfonamide substituted hydrazine derivatives as JAK kinase inhibitors | 启元生物(杭州)有限公司 | 2022-09-02 | — | — | CN | disclosed |