Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028661 | 0.80 | MCHR1 (0.59) | AGERMAPTMCOLN3PSEN1PSEN2 | |
| SCHEMBL1738729 | 0.79 | AGER (0.49) | AGERMAPTMCOLN3PSEN1PSEN2 | |
| SCHEMBL29028419 | 0.73 | ALDH1A1 (0.43) | AGERMAPTMCOLN3GLAMCHR1 | |
| SCHEMBL29800510 | 0.73 | TSHR (0.42) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2474059 | 0.72 | HTT (0.48) | MAPTGLAMCHR1CNR2ALDH1A1 | |
| SCHEMBL28950498 | 0.72 | PSEN1 (0.42) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29028669 | 0.71 | MMP2 (0.46) | AGERMAPTMCOLN3GLAMCHR1 | |
| SCHEMBL29028428 | 0.71 | CNR2 (0.57) | MCHR1CNR2ALDH1A1CA12CA9 | |
| SCHEMBL28950496 | 0.71 | APOBEC3G (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28830679 | 0.70 | HPGD (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957120-A | Alkenyl homopiperidine compound and preparation method thereof | 苏州大学 | 2022-08-30 | — | — | CN | disclosed |