Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL28423364 | 0.94 | LMNA (0.62) | LMNACA1ALDH1A1CA4ALOX15 | |
| Acrylic Acid SCHEMBL27591473 | 0.87 | LMNA (0.71) | LMNACA1ALDH1A1CA4ALOX15 | |
| Acrylic Acid SCHEMBL9769256 | 0.87 | LMNA (0.71) | LMNACA1ALDH1A1CA4ALOX15 | |
| Acrylic Acid SCHEMBL9769250 | 0.87 | LMNA (0.71) | LMNACA1ALDH1A1CA4ALOX15 | |
| Methacrylic Acid SCHEMBL8412858 | 0.86 | LMNA (0.53) | LMNACA1ALDH1A1CA4ALOX15 | |
| Acrylic Acid SCHEMBL4277400 | 0.84 | LMNA (0.67) | LMNACA1ALDH1A1CA4ALOX15 | |
| Acrylic Acid SCHEMBL3273150 | 0.84 | CA1 (0.60) | LMNACA1ALDH1A1CA4TSHR | |
| Acrylic Acid SCHEMBL1950662 | 0.83 | LMNA (0.77) | LMNAALDH1A1ALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL475312 | 0.83 | — | — | |
| Acrylic Acid SCHEMBL8143061 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114848529-A | SOD rose repair moisturizing cream | 云南花之流健康产业发展股份有限公司 | 2022-08-05 | — | — | CN | disclosed |