Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.35 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL15608360 | 0.97 | LMNA (0.62) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL16617487 | 0.94 | LMNA (0.59) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL29771275 | 0.93 | LMNA (0.67) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL29159583 | 0.93 | LMNA (0.67) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL5071458 | 0.93 | LMNA (0.67) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL11349872 | 0.93 | LMNA (0.67) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL29632709 | 0.93 | LMNA (0.67) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL15843882 | 0.93 | LMNA (0.67) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL9766312 | 0.90 | LMNA (0.62) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL28571331 | 0.90 | LMNA (0.62) | LMNAALOX15HSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115770417-A | Defoaming thickener for concentration treatment of cyclohexanone waste alkali | 中石化南京化工研究院有限公司 | 2023-03-10 | — | — | CN | claimed |
| EP-1411874-B2 | ABSORBENT BODIES FOR APPLYING TO SKIN AND MUCUSA SURFACES | BSN MEDICAL GMBH (DE) | 2019-11-20 | — | — | EP | claimed |
| CN-110464660-A | It a kind of anti-ageing crease-resistant ink-jet ink and preparation method thereof and is applied in customized facial mask | LI HEWEI | 2019-11-19 | — | — | CN | claimed |
| CN-110433110-A | It is a kind of can the drying of spray printing moisten ink-jet ink and its preparation method and application | LI HEWEI | 2019-11-12 | — | — | CN | claimed |
| CN-110403831-A | A kind of functionality antiallergic barrier ink-jet ink and its preparation method and application | LI HEWEI | 2019-11-05 | — | — | CN | claimed |
| EP-1411874-B1 | ABSORBENT BODIES FOR APPLYING TO SKIN AND MUCUSA SURFACES | BSN MEDICAL GMBH (DE) | 2016-04-13 | — | — | EP | claimed |
| EP-0801560-B1 | A CONTROLLED RELEASE DRUG SUSPENSION DELIVERY DEVICE | MERCK & CO INC (US) | 2003-07-02 | — | — | EP | claimed |
| EP-0801560-A4 | A CONTROLLED RELEASE DRUG SUSPENSION DELIVERY DEVICE | MERCK & CO INC (US) | 1998-08-19 | — | — | EP | claimed |
| EP-0801560-A1 | A CONTROLLED RELEASE DRUG SUSPENSION DELIVERY DEVICE | Merck & Co., Inc. (US) | 1997-10-22 | — | — | EP | claimed |
| WO-1996019201-A1 | A CONTROLLED RELEASE DRUG SUSPENSION DELIVERY DEVICE | MERCK & CO., INC. (US) | 1996-06-27 | — | — | WO | claimed |
| US-20240399329-A1 | CROSSLINKED MULTILAYERED MATERIAL COMPOSITIONS, METHODS FOR THEIR PREPARATION AND APPLICATIONS THEREOF | PATHAK HOLDINGS LLC | 2024-12-05 | — | — | US | disclosed |
| EP-4301827-A1 | CHEMICAL ADDITIVES FOR ENHANCING THE PERFORMANCE OF FRICTION REDUCER SOLUTION AND ITS APPLICATIONS THEREOF | Liu, Feipeng (US) | 2024-01-10 | — | — | EP | disclosed |
| CN-116807755-A | Composite absorption core of paper diaper and application thereof | 杭州可靠护理用品股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023139283-A1 | WOUND DRESSING HAVING ARCUATE INDENTATIONS | LOHMANN & RAUSCHER GMBH (AT) | 2023-07-27 | — | — | WO | disclosed |
| CN-115770417-A | Defoaming thickener for concentration treatment of cyclohexanone waste alkali | 中石化南京化工研究院有限公司 | 2023-03-10 | — | — | CN | disclosed |
| EP-0697217-A1 | High performance super-absorbent material and absorbent devices containing the same | PEARLSTEIN, Leonard (US) | 1996-02-21 | — | — | EP | disclosed |
| WO-1996004024-A1 | HIGH PERFORMANCE SUPERABSORBENT MATERIAL AND ABSORBENT DEVICES CONTAINING THE SAME | PEARLSTEIN LEONARD (US) | 1996-02-15 | — | — | WO | disclosed |
| EP-0055848-B1 | A WATER-ABSORBING RUBBER COMPOSITION | KURARAY CO., LTD. (JP) | 1984-07-25 | — | — | EP | disclosed |
| US-4420588-A | BLEND OF 1,3 DIENE RUBBER WITH CROSSLINKED POLYMER OF AN UNSATURATED COMPOUND AND A EPOXY OR AMINE COMPOUND | KURARAY COMPANY LIMITED (JP) | 1983-12-13 | — | — | US | disclosed |
| EP-0055848-A2 | A water-absorbing rubber composition | KURARAY CO., LTD. (JP) | 1982-07-14 | — | — | EP | disclosed |