Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3432676 | 0.78 | GRM5 (0.37) | CA2CA9HAO1CA1 | |
| SCHEMBL28196135 | 0.76 | GRM5 (0.43) | CYP2A6CA2ALDH1A1CA12CA9 | |
| SCHEMBL27722306 | 0.76 | APP (0.48) | KIF11CA2ALDH1A1CA12CA3 | |
| SCHEMBL22353122 | 0.76 | APP (0.59) | KIF11ALDH1A1TSHRHAO1MAOB | |
| SCHEMBL28624467 | 0.76 | CYP2A6 (0.38) | CYP2A6CA2ALDH1A1CA9HAO1 | |
| SCHEMBL31380183 | 0.76 | APP (0.36) | HAO1 | |
| SCHEMBL28832028 | 0.76 | KCNH2 (0.39) | CYP2A6ALDH1A1CYP19A1HAO1MAOA | |
| SCHEMBL507497 | 0.76 | KIF11 (0.48) | KIF11CYP2A6CA2ALDH1A1CA12 | |
| SCHEMBL10300311 | 0.76 | CA2 (0.58) | KIF11CYP2A6CA2ALDH1A1CA12 | |
| SCHEMBL5607030 | 0.76 | CA2 (0.58) | KIF11CYP2A6CA2ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490461-A | Trifluoromethyl substituted quinazolinone compound, preparation method and application | 平顶山学院 | 2025-02-21 | — | — | CN | disclosed |
| CN-114702504-B | Trifluoromethyl substituted indolopyranone compound, preparation method thereof and application thereof in antitumor drugs | 平顶山学院 | 2023-04-07 | — | — | CN | disclosed |
| CN-114702504-A | Trifluoromethyl substituted indolopyranone compound, preparation method thereof and application thereof in antitumor drugs | 平顶山学院 | 2022-07-05 | — | — | CN | disclosed |