Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | STK10 | O94804 | 1/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454133 | 0.83 | MEN1 (0.37) | L3MBTL1ALDH1A1HSD17B10TSHRNPC1 | |
| SCHEMBL28737053 | 0.77 | MEN1 (0.39) | L3MBTL1ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6849472 | 0.76 | L3MBTL1 (0.36) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27902284 | 0.73 | THRB (0.36) | L3MBTL1ALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL4619747 | 0.69 | HDAC4 (0.33) | ALDH1A1HPGDTDP1DHODHNPC1 | |
| SCHEMBL28902464 | 0.68 | KDM4E (0.31) | KDM4E | |
| SCHEMBL7551777 | 0.68 | ALDH1A1 (0.33) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL28852266 | 0.67 | HDAC4 (0.31) | NPC1RAB9A | |
| SCHEMBL28418518 | 0.67 | POLB (0.33) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29000968 | 0.67 | NPC1 (0.41) | L3MBTL1ALDH1A1HPGDHSD17B10HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702444-A | AHA1 inhibitor with multiple myeloma resisting effect and preparation method and application thereof | 南京中医药大学 | 2022-07-05 | — | — | CN | disclosed |