Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28831998 | 0.91 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EKMT2AMAPTDRD2 | |
| SCHEMBL29143300 | 0.78 | HTR6 (0.44) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL11999976 | 0.75 | MEN1 (0.52) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL5040066 | 0.74 | HTR6 (0.47) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL12002188 | 0.69 | HTR6 (0.50) | ALDH1A1KDM4EKMT2AMEN1HTR6 | |
| SCHEMBL2799840 | 0.68 | HTR6 (0.47) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL28294733 | 0.67 | HDAC1 (0.53) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL2797396 | 0.66 | HTR6 (0.47) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL4225409 | 0.65 | PTGER3 (0.49) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28832153 | 0.64 | MAPT (0.46) | ALDH1A1LMNAKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702444-A | AHA1 inhibitor with multiple myeloma resisting effect and preparation method and application thereof | 南京中医药大学 | 2022-07-05 | — | — | CN | disclosed |