Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCND2 | P30279 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11999976 | 0.86 | MEN1 (0.52) | HTR6KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL5040066 | 0.85 | HTR6 (0.47) | HTR6CCR2KDM4EMAPTALDH1A1 | |
| SCHEMBL28831998 | 0.81 | SMN1; SMN2 (0.41) | HTR6KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL12002188 | 0.79 | HTR6 (0.50) | HTR6CCR2KDM4ECDK4CCND1 | |
| SCHEMBL28832015 | 0.78 | ALDH1A1 (0.38) | HTR6KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL2799840 | 0.78 | HTR6 (0.47) | HTR6CCR2KDM4EMAPTALDH1A1 | |
| SCHEMBL2797396 | 0.75 | HTR6 (0.47) | HTR6CCR2KDM4EMAPTALDH1A1 | |
| SCHEMBL98218 | 0.72 | CYP19A1 (0.54) | HTR6KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL4225409 | 0.72 | PTGER3 (0.49) | KDM4ECDK4CCND1CCND2CCND3 | |
| SCHEMBL2800552 | 0.68 | HTR6 (0.39) | HTR6CCR2KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186001-A | AHA1 inhibitor with multiple myeloma-resisting activity and preparation method and application thereof | 南京中医药大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-114702444-B | AHA1 inhibitor with multiple myeloma resistance and preparation method and application thereof | 南京中医药大学 | 2023-09-12 | — | — | CN | disclosed |