Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prometryn SCHEMBL7657627 | 0.80 | MAPK1 (0.56) | SMN1; SMN2TSHRHSD17B10MAPK1CYP2C9 | |
| Prometryn SCHEMBL7622 | 0.80 | MAPK1 (0.56) | SMN1; SMN2TSHRHSD17B10MAPK1CYP2C9 | |
| Prometryn SCHEMBL19463434 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRHSD17B10MAPK1CYP2C9 | |
| Prometryn SCHEMBL367101 | 0.79 | MAPK1 (0.58) | SMN1; SMN2TSHRHSD17B10MAPK1CYP2C9 | |
| SCHEMBL10957595 | 0.79 | MAPK1 (0.47) | SMN1; SMN2TSHRHSD17B10MAPK1CYP2C9 | |
| Prometryn SCHEMBL20723870 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRHSD17B10MAPK1CYP2C9 | |
| Prometryn SCHEMBL20723889 | 0.78 | GAA (0.58) | SMN1; SMN2TSHRHSD17B10MAPK1ALDH1A1 | |
| Prometryn SCHEMBL5542826 | 0.77 | TSHR (0.48) | SMN1; SMN2TSHRHSD17B10MAPK1CYP2C9 | |
| Ametryne SCHEMBL18115242 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2TSHRHSD17B10CYP2C9ALDH1A1 | |
| SCHEMBL29435432 | 0.73 | MAPK1 (0.50) | SMN1; SMN2TSHRHSD17B10MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853687-A | Prometryn hapten, complete antigen, antibody, preparation method and application | 中国农业科学院农业质量标准与检测技术研究所 | 2022-08-05 | — | — | CN | disclosed |