Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16829343 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1SIGMAR1PKM | |
| SCHEMBL28092846 | 0.81 | MEN1 (0.58) | ALDH1A1KMT2AMEN1SIGMAR1PKM | |
| SCHEMBL28476701 | 0.81 | PKM (0.44) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL16691260 | 0.79 | GAA (0.54) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL14574198 | 0.78 | MAPT (0.57) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL5813426 | 0.77 | ALDH1A1 (0.87) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL23259569 | 0.77 | PIK3CD (0.47) | ALDH1A1KMT2AMAPTSMN1; SMN2PIK3CA | |
| SCHEMBL21410615 | 0.77 | PIK3CD (0.47) | ALDH1A1KMT2AMEN1MAPTPIK3CA | |
| SCHEMBL30785733 | 0.77 | PIK3CD (0.47) | ALDH1A1KMT2AMEN1MAPTPIK3CA | |
| SCHEMBL2376923 | 0.76 | SIGMAR1 (0.76) | ALDH1A1KMT2AMEN1MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029651-A | Urea derivatives as kinase inhibitors | 瑞斯比维特有限公司 | 2016-10-12 | — | — | CN | disclosed |