Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DBH | P09172 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907136 | 0.85 | MEN1 (0.43) | GAAMEN1KMT2AFOLH1CA12 | |
| SCHEMBL5613911 | 0.84 | CA12 (0.51) | GAAMEN1KMT2ACA12CA1 | |
| SCHEMBL29446275 | 0.84 | CA12 (0.51) | GAAMEN1KMT2ACA12CA1 | |
| SCHEMBL27842836 | 0.82 | PGR (0.39) | KDM4ENPSR1TSHR | |
| SCHEMBL28096908 | 0.81 | MAPT (0.45) | GAAKDM4ETSHR | |
| SCHEMBL27669886 | 0.79 | PTGS1 (0.42) | MEN1KMT2ATSHR | |
| SCHEMBL3337932 | 0.79 | TSHR (0.58) | GAAMEN1KMT2ABLMNPSR1 | |
| SCHEMBL334274 | 0.78 | TRPA1 (0.56) | GAAMEN1KMT2ACA12CA1 | |
| SCHEMBL29510759 | 0.77 | CYP1A2 (0.50) | CYP19A1TSHR | |
| SCHEMBL29510782 | 0.77 | CYP1A2 (0.50) | CYP19A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011021-B | heterocyclic derivatives and their use as prostaglandin D2 receptor modulators | 埃科特莱茵药品有限公司 | 2016-08-24 | — | — | CN | disclosed |