SCHEMBL10907136

SCHEMBL10907136

CC(=O)OC(OC(C)=O)c1ccc(O)c(Br)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
FOLH1 Q04609 1/20 0.40
ALOX15 P16050 2/20 0.39
CYP19A1 P11511 1/20 0.39
BLM P54132 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 1/20 0.38
ESR1 P03372 1/20 0.38
ALDH1A1 P00352 1/20 0.37
CYP3A4 P08684 1/20 0.37
MET P08581 2/20 0.36
MKNK2 Q9HBH9 1/20 0.35
NR3C1 P04150 2/20 0.34
PGR P06401 1/20 0.34
AR P10275 1/20 0.34
ALOX12 P18054 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9516729 0.86 ALDH1A1 (0.39) GAAFOLH1CYP19A1BLMNPSR1
SCHEMBL28833648 0.85 GAA (0.42) MEN1GAAKMT2AFOLH1ALOX15
SCHEMBL677823 0.84 CA12 (0.44) MEN1GAAKMT2AALOX15BLM
SCHEMBL10908717 0.79 LMNA (0.43) BLMNPSR1TSHRESR1ALDH1A1
SCHEMBL10907121 0.78 ALOX15 (0.45) MEN1GAAKMT2AFOLH1ALOX15
SCHEMBL19354231 0.77 PKM (0.51) TSHR
SCHEMBL17863579 0.77 ALDH1A1 (0.48) BLMNPSR1TSHRALDH1A1CYP3A4
SCHEMBL27937248 0.76 CYP1A2 (0.52) CYP19A1TSHRALDH1A1CYP3A4
SCHEMBL11809690 0.74 ESR1 (0.44) MEN1KMT2AALOX15BLMNPSR1
SCHEMBL20879477 0.73 TDP1 (0.41) KMT2ATSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4588835-A Process for preparing alkoxyphenols OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1986-05-13 US disclosed