SCHEMBL2883365

SCHEMBL2883365

CO[Si](CCCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(OC)OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.49
CA2 P00918 3/20 0.49
CA1 P00915 2/20 0.49
ALDH1A1 P00352 7/20 0.45
TSHR P16473 3/20 0.45
LMNA P02545 2/20 0.45
KMT2A Q03164 3/20 0.44
MAPK1 P28482 3/20 0.44
MEN1 O00255 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
BLM P54132 2/20 0.44
ATM Q13315 2/20 0.44
HIF1A Q16665 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
GMNN O75496 1/20 0.44
GABBR2 O75899 1/20 0.44
TP53 P04637 1/20 0.44
CYP2C9 P11712 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2883418 0.86 GAA (0.48) GAACA2CA1ALDH1A1TSHR
SCHEMBL14174487 0.84 GAA (0.47) GAACA2CA1ALDH1A1TSHR
SCHEMBL13871634 0.81 GAA (0.67) GAAALDH1A1LMNAKMT2AMEN1
SCHEMBL14174489 0.81 GAA (0.47) GAACA2CA1KMT2AMEN1
SCHEMBL14174490 0.81 CA2 (0.42) GAACA2CA1ALDH1A1TSHR
SCHEMBL8751536 0.80 ALDH1A1 (0.59) GAACA2CA1ALDH1A1TSHR
SCHEMBL283499 0.80 ALDH1A1 (0.59) GAACA2CA1ALDH1A1TSHR
SCHEMBL2879172 0.79 CA2 (0.56) GAACA2CA1ALDH1A1TSHR
SCHEMBL8751548 0.79 ALDH1A1 (0.57) GAACA2CA1ALDH1A1TSHR
SCHEMBL17588977 0.79 ALDH1A1 (0.57) GAACA2CA1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60245653-A None JP disclosed
JP-61100587-A None JP disclosed
US-7799433-B2 Silicone-based pressure-sensitive adhesive and adhesive tape DOW CORNING TORAY COMPANY, LTD. (JP) 2010-09-21 US disclosed
US-20070299216-A1 Silicone-Based Pressure-Sensitive Adhesive and Adhesive Tape DOW CORNING TORAY COMPANY, LTD. (JP) 2007-12-27 US disclosed
WO-2006003853-A2 SILICONE-BASED PRESSURE-SENSITIVE ADHESIVE AND ADHESIVE TAPE DOW CORNING TORAY CO., LTD. (JP) 2006-01-12 WO disclosed
JP-S61100587-A ORGANOSILICON COMPOUND CHISSO CORP 1986-05-19 JP disclosed
JP-S60245653-A POLYOLEFIN RESIN COMPOSITION CHISSO CORP 1985-12-05 JP disclosed