Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375959 | 0.98 | LTA4H (0.36) | LTA4HNOS1NOS3NOS2SLC7A5 | |
| SCHEMBL2611908 | 0.98 | LTA4H (0.36) | LTA4HNOS1NOS3NOS2SLC7A5 | |
| SCHEMBL330114 | 0.98 | LTA4H (0.36) | LTA4HNOS1NOS3NOS2SLC7A5 | |
| Water SCHEMBL30283282 | 0.96 | LTA4H (0.36) | LTA4HNOS1NOS3NOS2SLC7A5 | |
| Hydrochloric Acid SCHEMBL6700549 | 0.96 | LTA4H (0.36) | LTA4HNOS1NOS3NOS2SLC7A5 | |
| Hydrochloric Acid SCHEMBL25276889 | 0.96 | LTA4H (0.36) | LTA4HNOS1NOS3NOS2SLC7A5 | |
| Hydrochloric Acid SCHEMBL6700554 | 0.96 | LTA4H (0.36) | LTA4HNOS1NOS3NOS2SLC7A5 | |
| Hydrochloric Acid SCHEMBL30947817 | 0.84 | KDM4E (0.38) | GRIK1PGDBHMTGABRR1LMNA | |
| SCHEMBL17732318 | 0.84 | PGD (0.37) | GRIK1PGDBHMTGABRR1LMNA | |
| SCHEMBL29720991 | 0.83 | DGAT1 (0.34) | NOS1NOS3NOS2SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045883-B | A kind of preparation method of aspartic acid -1- tert-butyl ester derivatives | 成都郑源生化科技有限公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-106045883-A | Preparation method of aspartic acid-1-tert-butyl ester derivative | 成都郑源生化科技有限公司 | 2016-10-26 | — | — | CN | disclosed |