Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 7/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BCL9 | O00512 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.36 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362332 | 0.86 | FKBP1A (0.45) | FKBP1AHTR2CHPGDALDH1A1TSHR | |
| SCHEMBL9367912 | 0.86 | FKBP1A (0.45) | FKBP1AHTR2CHPGDALDH1A1TSHR | |
| SCHEMBL28833932 | 0.83 | NOTUM (0.44) | HPGDALDH1A1CYP3A4SLC6A9 | |
| SCHEMBL28838606 | 0.77 | ALDH1A1 (0.45) | ALDH1A1POLBACE | |
| SCHEMBL7122146 | 0.76 | POLB (0.43) | FKBP1AHTR2CHPGDALDH1A1POLB | |
| SCHEMBL28975603 | 0.74 | FKBP1A (0.49) | FKBP1AHTR2CCYP2C19TSHR | |
| SCHEMBL28975604 | 0.74 | FKBP1A (0.49) | FKBP1AHTR2CCYP2C19TSHR | |
| SCHEMBL7125855 | 0.73 | FKBP1A (0.40) | FKBP1AHTR2CHPGDALDH1A1TSHR | |
| SCHEMBL7247064 | 0.73 | FKBP1A (0.40) | FKBP1AHTR2CHPGDALDH1A1TSHR | |
| SCHEMBL28838626 | 0.73 | S1PR1 (0.40) | CHRM3ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114980976-A | Covalent RAS inhibitors and uses thereof | 锐新医药公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114901366-A | RAS inhibitors | 锐新医药公司 | 2022-08-12 | — | — | CN | disclosed |