Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 11/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28975603 | 1.00 | FKBP1A (0.49) | FKBP1ASMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL7362332 | 0.86 | FKBP1A (0.45) | FKBP1ASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9367912 | 0.86 | FKBP1A (0.45) | FKBP1ASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL7122099 | 0.81 | FKBP1A (0.44) | FKBP1ACYP2C19HTR2CFABP7FABP5 | |
| SCHEMBL7122146 | 0.81 | POLB (0.43) | FKBP1AHTR2CFABP7FABP5 | |
| SCHEMBL2771369 | 0.80 | KMT2A (0.44) | FKBP1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28457749 | 0.80 | KMT2A (0.44) | FKBP1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL25971417 | 0.78 | FKBP1A (0.49) | FKBP1ASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL5688777 | 0.78 | ALDH1A1 (0.40) | SMN1; SMN2 | |
| SCHEMBL5688772 | 0.78 | ALDH1A1 (0.40) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916194-A | Methods for delaying, preventing and treating acquired resistance to RAS inhibitors | 锐新医药公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115873020-A | RAS inhibitors | 锐新医药公司 | 2023-03-31 | — | — | CN | disclosed |