Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933518 | 1.00 | USP30 (0.48) | USP30IDH1PIM1PIM2HDAC4 | |
| SCHEMBL28833998 | 1.00 | USP30 (0.48) | USP30IDH1PIM1PIM2HDAC4 | |
| SCHEMBL28833986 | 1.00 | USP30 (0.48) | USP30IDH1PIM1PIM2HDAC4 | |
| SCHEMBL29933501 | 1.00 | USP30 (0.48) | USP30IDH1PIM1PIM2HDAC4 | |
| SCHEMBL23360477 | 0.94 | ALDH1A1 (0.47) | USP30IDH1PIM1PIM2HDAC4 | |
| SCHEMBL29862739 | 0.94 | ALDH1A1 (0.47) | USP30IDH1PIM1PIM2HDAC4 | |
| SCHEMBL29862606 | 0.93 | USP30 (0.49) | USP30IDH1PIM1PIM2HDAC4 | |
| SCHEMBL28834227 | 0.93 | USP30 (0.49) | USP30IDH1PIM1PIM2HDAC4 | |
| SCHEMBL29862973 | 0.93 | USP30 (0.49) | USP30IDH1PIM1PIM2HDAC4 | |
| SCHEMBL28834126 | 0.93 | USP30 (0.49) | USP30IDH1PIM1PIM2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |