SCHEMBL29933501

SCHEMBL29933501

CC(C)(C)OC(=O)N1CC[C@H](Nc2ccnc3c(C(F)(F)F)cccc23)C1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 7/20 0.48
IDH1 O75874 1/20 0.47
PIM1 P11309 2/20 0.46
PIM2 Q9P1W9 2/20 0.46
HDAC4 P56524 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
PARP1 P09874 1/20 0.45
BTK Q06187 1/20 0.44
CNR1 P21554 2/20 0.44
RIPK1 Q13546 1/20 0.43
TRPV1 Q8NER1 1/20 0.43
BRD4 O60885 1/20 0.43
PIK3CD O00329 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29933518 1.00 USP30 (0.48) USP30IDH1PIM1PIM2HDAC4
SCHEMBL28833987 1.00 USP30 (0.48) USP30IDH1PIM1PIM2HDAC4
SCHEMBL28833998 1.00 USP30 (0.48) USP30IDH1PIM1PIM2HDAC4
SCHEMBL28833986 1.00 USP30 (0.48) USP30IDH1PIM1PIM2HDAC4
SCHEMBL23360477 0.94 ALDH1A1 (0.47) USP30IDH1PIM1PIM2HDAC4
SCHEMBL29862739 0.94 ALDH1A1 (0.47) USP30IDH1PIM1PIM2HDAC4
SCHEMBL29862606 0.93 USP30 (0.49) USP30IDH1PIM1PIM2HDAC4
SCHEMBL28834227 0.93 USP30 (0.49) USP30IDH1PIM1PIM2HDAC4
SCHEMBL29862973 0.93 USP30 (0.49) USP30IDH1PIM1PIM2HDAC4
SCHEMBL28834126 0.93 USP30 (0.49) USP30IDH1PIM1PIM2HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP disclosed
US-11655235-B2 Pyrrolidine and piperidine compounds YUHAN CORPORATION (KR) 2023-05-23 US disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655235-B2 Pyrrolidine and piperidine compounds FAP, APC, VHL USP30 1231/4885IDH1 943/4885PIM1 1984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.