SCHEMBL29862973

SCHEMBL29862973

CC(C)(C)OC(=O)N1CC[C@H](Nc2ccc(C(F)(F)F)c3ncccc23)C1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 5/20 0.49
HDAC4 P56524 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
TLR7 Q9NYK1 1/20 0.45
IDH1 O75874 1/20 0.45
TRPV1 Q8NER1 1/20 0.45
PIM1 P11309 2/20 0.45
PIM2 Q9P1W9 2/20 0.45
BTK Q06187 1/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
HSD11B1 P28845 2/20 0.44
SFRP1 Q8N474 2/20 0.44
CYP2D6 P10635 1/20 0.44
CNR1 P21554 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28834126 1.00 USP30 (0.49) USP30HDAC4HDAC6TLR7IDH1
SCHEMBL28834227 1.00 USP30 (0.49) USP30HDAC4HDAC6TLR7IDH1
SCHEMBL29862606 1.00 USP30 (0.49) USP30HDAC4HDAC6TLR7IDH1
SCHEMBL28834128 1.00 USP30 (0.49) USP30HDAC4HDAC6TLR7IDH1
SCHEMBL23360027 0.94 ALDH1A1 (0.47) USP30HDAC4TLR7IDH1SFRP1
SCHEMBL28833998 0.93 USP30 (0.48) USP30HDAC4HDAC6IDH1TRPV1
SCHEMBL28833987 0.93 USP30 (0.48) USP30HDAC4HDAC6IDH1TRPV1
SCHEMBL29933518 0.93 USP30 (0.48) USP30HDAC4HDAC6IDH1TRPV1
SCHEMBL29933501 0.93 USP30 (0.48) USP30HDAC4HDAC6IDH1TRPV1
SCHEMBL28833986 0.93 USP30 (0.48) USP30HDAC4HDAC6IDH1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP disclosed
CN-114867719-B Pyrrolidine and piperidine compounds 柳韩洋行 2024-06-25 CN disclosed
US-11655235-B2 Pyrrolidine and piperidine compounds YUHAN CORPORATION (KR) 2023-05-23 US disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed
CN-114867719-A Pyrrolidine and piperidine compounds 柳韩洋行 2022-08-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655235-B2 Pyrrolidine and piperidine compounds FAP, APC, VHL USP30 1231/4885HDAC4 1662/4885HDAC6 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.