Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28098761 | 0.88 | ALDH1A1 (0.43) | TSHRLMNATP53ALOX15ALDH1A1 | |
| SCHEMBL28098688 | 0.87 | HRH3 (0.42) | TSHRLMNATP53ALOX15ALDH1A1 | |
| SCHEMBL30006358 | 0.86 | ALDH1A1 (0.56) | TSHRTP53ALDH1A1HPGDMEN1 | |
| SCHEMBL20980044 | 0.86 | ALDH1A1 (0.56) | TSHRTP53ALDH1A1HPGDMEN1 | |
| SCHEMBL13342918 | 0.78 | CYP1A2 (0.62) | TSHRLMNATP53ALOX15ALDH1A1 | |
| SCHEMBL22372611 | 0.77 | USP30 (0.56) | TSHRLMNATP53ALOX15ALDH1A1 | |
| SCHEMBL829543 | 0.75 | MAPT (0.46) | TSHRLMNATP53ALOX15ALDH1A1 | |
| SCHEMBL28098637 | 0.72 | ALDH1A1 (0.43) | TSHRLMNATP53ALOX15ALDH1A1 | |
| SCHEMBL28098625 | 0.72 | LMNA (0.54) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL29617486 | 0.71 | MEN1 (0.58) | TSHRLMNATP53ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884657-A | Nitrogen Formyloxy-substituted chlorobenzophenone derivative | 山西医科大学 | 2016-08-24 | — | — | CN | claimed |
| CN-105884657-A | Nitrogen Formyloxy-substituted chlorobenzophenone derivative | 山西医科大学 | 2016-08-24 | — | — | CN | disclosed |