Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20980044 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KDM4EGAANPSR1 | |
| SCHEMBL28834161 | 0.86 | TSHR (0.52) | ALDH1A1GAANPSR1TP53MEN1 | |
| SCHEMBL28098688 | 0.83 | HRH3 (0.42) | ALDH1A1NPSR1TP53MAPTTSHR | |
| SCHEMBL28098761 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TP53MEN1MAPTKMT2A | |
| SCHEMBL30514597 | 0.81 | KDM4E (0.48) | ALDH1A1KDM4EMEN1CYP3A4MAPT | |
| SCHEMBL13342919 | 0.77 | RAB9A (0.62) | ALDH1A1HSD17B10KDM4EGAANPSR1 | |
| SCHEMBL22372574 | 0.77 | HSD17B10 (0.59) | ALDH1A1HSD17B10KDM4EGAANPSR1 | |
| SCHEMBL6101008 | 0.77 | POLB (0.54) | ALDH1A1HSD17B10KDM4EGAANPSR1 | |
| SCHEMBL19627242 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HSD17B10GAANPSR1MEN1 | |
| SCHEMBL13342935 | 0.75 | POLB (0.60) | ALDH1A1HSD17B10KDM4EGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115212192-A | Application of benzophenone derivative in preparation of anti-renal fibrosis medicine | 山西医科大学 | 2022-10-21 | — | — | CN | disclosed |