Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697907 | 0.85 | LMNA (0.50) | PDE10ACYSLTR1CYSLTR2LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL28965875 | 0.83 | ADRA2A (0.50) | PDE10ACYSLTR1CYSLTR2LMNACYP1A2 | |
| SCHEMBL3267444 | 0.76 | CYSLTR1 (0.57) | PDE10ACYSLTR1CYSLTR2LMNACYP1A2 | |
| SCHEMBL30879956 | 0.76 | CYSLTR1 (0.57) | PDE10ACYSLTR1CYSLTR2LMNACYP1A2 | |
| SCHEMBL11731214 | 0.75 | NCF1 (0.47) | PDE10ACYSLTR1CYSLTR2LMNACYP1A2 | |
| SCHEMBL28818198 | 0.75 | CYP1A2 (0.45) | PDE10ACYSLTR1CYSLTR2LMNACYP1A2 | |
| SCHEMBL4938792 | 0.74 | CYSLTR1 (0.55) | PDE10ACYSLTR1CYSLTR2LMNAGPBAR1 | |
| (Chloromethyl)Benzene SCHEMBL27991911 | 0.74 | LMNA (0.41) | PDE10ACYSLTR1CYSLTR2LMNAGPBAR1 | |
| SCHEMBL1881275 | 0.72 | CYP1A2 (0.43) | PDE10ACYSLTR1CYSLTR2LMNAGPBAR1 | |
| SCHEMBL4281890 | 0.72 | KMT2A (0.58) | PDE10ALMNAALDH1A1GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103857656-B | Enantioselective process for insecticidal 3-aryl-3-trifluoromethyl-substituted pyrrolidines | 先正达参股股份有限公司 | 2016-09-14 | — | — | CN | disclosed |